Viagra With Dapoxetine
Viagra With Dapoxetine
- Available from pharmacies and online suppliers — legally this combination is prescription‑only in regulated markets, but in practice some pharmacies and many online/e‑pharmacies (especially outside strict jurisdictions) may supply “viagra with dapoxetine” without a prescription or as an unlicensed generic, usually in discreet blister packs.
- Used to treat men with both erectile dysfunction (ED) and premature ejaculation (PE); Sildenafil is a phosphodiesterase‑5 (PDE5) inhibitor that increases penile blood flow to support erection, and Dapoxetine is a short‑acting selective serotonin reuptake inhibitor (SSRI) that delays ejaculation.
- The usual starting dose is Sildenafil 100 mg + Dapoxetine 60 mg taken 1–3 hours before sexual activity; other marketed strengths include 50 mg/30 mg and 100 mg/30 mg. Do not take more than one dose in 24 hours.
- Oral administration as film‑coated tablets, typically supplied in blister strips of 4 or 10 tablets.
- Sildenafil commonly begins to work within 30–60 minutes; Dapoxetine’s effect on ejaculation control is seen within 1–3 hours — the combination is therefore usually taken 1–3 hours before sex.
- Duration of action: Sildenafil’s effect lasts around 4–5 hours (up to about 6 hours for some men); Dapoxetine’s pharmacological effect is short (around 4 hours), so the combined clinical benefit is generally within a 4–6 hour window after dosing.
- Alcohol warning: avoid excessive alcohol when using this combination — alcohol increases the risk of dizziness, fainting, low blood pressure, impaired judgement and may worsen side effects (and can reduce sexual performance); minimise or avoid alcohol around the time of dosing.
- The most common side effects include headache, nausea, dizziness/orthostatic hypotension, flushing, nasal congestion, dyspepsia, insomnia and dry mouth; seek urgent care for priapism (erection >4 hours), severe hypotension, agitation or signs of serotonin syndrome.
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Basic Viagra With Dapoxetine Information
- INN (International Nonproprietary Name): Sildenafil (a phosphodiesterase type 5 inhibitor) and Dapoxetine (a selective serotonin reuptake inhibitor).
- Brand Names Available In Australia: Common global brands include Super P-Force, Sildigra Super Power, Manforce Duralong, Extra Super Tadarise and generic Sildenafil Dapoxetine tablets; Priligy is the reference brand for dapoxetine monotherapy.
- ATC Code: The fixed combination has no unique WHO ATC code listed in the raw data.
- Forms & Dosages: Oral film-coated tablets in blister strips (usually 4 or 10). Typical fixed strengths include 100 mg Sildenafil + 60 mg Dapoxetine, 50 mg + 30 mg and 100 mg + 30 mg.
- Manufacturers In Australia: No Australian manufacturers listed in the source data; major global suppliers are Indian companies such as Sunrise Remedies, Fortune Healthcare, Centurion Laboratories and Ajanta Pharma that supply the product through international distribution and online pharmacies.
- Registration Status In Australia: The fixed-dose combination is not approved by FDA or EMA and has variable registration worldwide; Sildenafil and Dapoxetine are individually approved in many jurisdictions but fixed combinations may be unregistered in Australia and supplied via private importation or unregistered authorised supply.
- OTC / Rx Classification: Prescription-only (Rx) in regulated markets according to the source data.
Latest Research Highlights
Men ask whether combining sildenafil and dapoxetine actually helps both erection and ejaculation timing.
Recent randomised controlled trials and systematic reviews from 2022–2025 consistently report that combined therapy improves erectile function and prolongs ejaculation latency compared with monotherapy in men with coexisting erectile dysfunction (ED) and premature ejaculation (PE).
Improvement has been measured as better IIEF scores and increased IELT in trials summarised in the source data.
Benefits reported include increased IELT, higher partner satisfaction and improved confidence during intercourse.
Harms reported across pooled studies include transient dizziness, orthostatic hypotension, nausea and visual symptoms; rare serotoninergic events such as agitation and very uncommon suicidal ideation have been associated with dapoxetine.
Regulatory authorities have not approved fixed-dose sildenafil+dapoxetine combinations at FDA/EMA level, and fixed-dose products remain variably registered worldwide, so clinicians should remain vigilant.
Australian clinicians should consider population differences such as cardiovascular disease prevalence and alcohol or recreational drug use patterns when applying trial data to patients in Australia.
Data Highlights
- INN: Sildenafil + Dapoxetine.
- Common fixed-dose used in trials and marketed products: 100 mg sildenafil + 60 mg dapoxetine (Rx-only).
- Serious adverse events noted in pooled safety signals: orthostatic hypotension, significant mood changes and rare serotoninergic effects.
| Outcome | Direction (Combo Vs Monotherapy) | Numeric Result |
|---|---|---|
| IELT (Ejaculation Latency) | Increase | Not specified in the supplied data |
| IIEF (Erectile Function) | Improvement | Not specified in the supplied data |
| Adverse Event Rate | Higher with combination (mild–moderate events) | Not specified in the supplied data |
Clinical Effectiveness In Australia
Patients commonly wonder if the combined pill will work better than taking two medicines separately.
Evidence indicates meaningful symptom improvement for men with concurrent ED and PE when using combined sildenafil + dapoxetine compared with single-agent therapy.
Effectiveness in Australian practice is judged on functional outcomes such as sexual confidence, relationship satisfaction and ability to complete intercourse.
Local safety monitoring uses the TGA adverse event reporting scheme, and clinicians are encouraged to report suspected adverse reactions.
Cost and access affect adherence in Australia because fixed-dose combinations are generally not PBS-listed, so patients often face full private costs.
Sildenafil is an established registered agent in Australia, while fixed-dose combinations may be unregistered and supplied via authorised unapproved medicines, private importation or telehealth pathways.
- Starting-dose guidance used in practice: 100 mg sildenafil + 60 mg dapoxetine, taken on-demand, no more than once per 24 hours.
- Clinical monitoring commonly includes cardiovascular assessment and mood screening before initiating therapy.
| Endpoint | Monotherapy | Combination |
|---|---|---|
| IELT | Improved with dapoxetine; estimates not specified | Further increase vs monotherapy; numeric data not specified |
| IIEF | Improved with sildenafil; estimates not specified | Improved more with combination in trials; numeric data not specified |
| AE Incidence | Lower vs combo for some events | Higher mild–moderate AE burden; serious AEs rare |
Indications And Expanded Uses
Many men ask when the combined tablet is an appropriate option.
Primary indication is adult men with coexisting ED and PE who have not obtained satisfactory control with single-agent therapy.
Expanded or off‑label uses reported internationally include trials in refractory PE and situational ED with performance anxiety, but evidence is limited.
Australian prescribers should document clinical rationale, obtain informed consent and screen for comorbid cardiovascular and psychiatric disorders before prescribing.
The fixed combination is not for women, adolescents or healthy men seeking performance enhancement.
Dosing is on‑demand for sexual activity, with short‑term trials of up to 3–6 months and periodic review being common practice.
Inclusion / Exclusion Checklist
- Include: Men ≥18 years with diagnosed ED and PE unresponsive to monotherapy.
- Exclude: Concurrent nitrate therapy, unstable cardiac disease, moderate–severe hepatic or renal impairment, bipolar disorder or history of suicidal ideation.
- Screen: CV risk, current antidepressant/serotonergic drugs, alcohol use and recreational drug use.
On‑Label Vs Off‑Label Definitions
- On‑Label: Use consistent with approved indications and local registration (sildenafil or dapoxetine monotherapy where approved).
- Off‑Label: Fixed‑dose combination use where the product is unregistered locally or for indications not supported by formal approval.
Composition And Brand Landscape
People often ask what exactly is in a combined tablet and which brands are common.
The active ingredients are sildenafil (a PDE5 inhibitor) and dapoxetine (a short‑acting SSRI used for PE).
Global brand names include Super P-Force, Sildigra Super Power, Manforce Duralong, Extra Super Tadarise and various generics.
Priligy remains the reference brand for dapoxetine monotherapy in many countries.
| Form | Dosages | Typical Brand Names |
|---|---|---|
| Oral Tablet | 100 mg Sildenafil + 60 mg Dapoxetine | Super P-Force, Sildigra Super Power |
| Oral Tablet | 50 mg Sildenafil + 30 mg Dapoxetine | Generic brands |
| Oral Tablet | 100 mg Sildenafil + 30 mg Dapoxetine | Snovitra Super Power, others |
Typical packaging is blister strips of 4 or 10 tablets with a patient leaflet.
ATC classification in source data: Sildenafil G04BE03 and Dapoxetine N06AB62; there is no unique ATC for the fixed combination.
Major manufacturers supplying global markets are predominantly Indian firms such as Sunrise Remedies, Fortune Healthcare, Centurion Laboratories and Ajanta Pharma.
Contraindications And Special Precautions
Patients often want to know the absolute no‑gos before taking the pill.
Absolute contraindications include known hypersensitivity to either ingredient, concurrent nitrate therapy and recent myocardial infarction or unstable cardiac disease.
Moderate–severe hepatic or renal impairment, bipolar disorder or major depression and history of suicidal ideation are additional absolute contraindications.
Relative precautions include elderly patients, concomitant alpha‑blocker or multiple antihypertensive therapy and those on MAO inhibitors where a 14‑day washout is required.
Indigenous and remote Australian patients commonly have higher baseline rates of cardiovascular disease and diabetes, so careful cardiovascular assessment is recommended before prescribing.
Daily‑life advice includes caution with driving or operating heavy machinery if dizziness or somnolence occur and avoidance of excessive alcohol before dosing.
Contraindications (Definition List)
- Absolute: Nitrate therapy, unstable cardiac disease, moderate–severe hepatic/renal impairment, bipolar disorder or suicidal history, hypersensitivity to ingredients.
- Relative: Concomitant alpha‑blockers, multiple antihypertensives, elderly patients, recent use of MAO inhibitors (14‑day washout).
Pre‑Prescription Screening Checklist
- Cardiovascular history including recent MI, angina or stroke.
- Current medications—especially nitrates, MAO inhibitors, potent CYP3A4 inhibitors and SSRIs.
- Mental health history—mood disorders or prior suicidal ideation.
- Liver and kidney function status.
- Alcohol and recreational drug use assessment.
Dosage Guidelines (Australian Clinical Practice)
Common practical question: how and when to take it for best effect.
The usual on‑demand starting dose used in trials and marketed combinations is sildenafil 100 mg plus dapoxetine 60 mg, taken 1–3 hours before sexual activity.
Alternative fixed strengths available include 50 mg/30 mg and 100 mg/30 mg.
Limit dosing frequency to not more than once every 24 hours.
Dose adjustments are often needed: lower starting doses or closer monitoring for elderly men and those with mild hepatic or renal impairment.
A combined trial of up to 3–6 months with periodic review may be considered for men who did not respond to dapoxetine alone.
| Patient Group | Suggested Dose/Action |
|---|---|
| Standard Adult | 100 mg Sildenafil + 60 mg Dapoxetine 1–3 hours before sex; ≤1 dose/24 h |
| Elderly | Consider lower dose or closer monitoring; assess BP and cardiac status |
| Moderate Hepatic/Renal Impairment | Avoid or use specialist advice; not recommended in moderate–severe impairment |
Counselling points include taking with a light meal because large fatty meals delay sildenafil absorption and avoiding excessive alcohol prior to dosing due to increased dizziness and hypotension risk.
Warnings: seek urgent care for priapism (erection >4 hours) and suspected overdose or severe hypotension.
Interactions Overview
Patients ask which other medicines can make this combination unsafe.
Major interactions of concern include nitrates (absolute contraindication because of severe hypotension) and additive blood‑pressure lowering with alpha‑blockers and multiple antihypertensives.
Potent CYP3A4 inhibitors such as ritonavir and ketoconazole can substantially increase sildenafil exposure and require caution or avoidance.
MAO inhibitors and other serotonergic medicines increase the risk of serotonin syndrome when combined with dapoxetine and a 14‑day washout is recommended after MAOI therapy.
Alcohol and grapefruit juice can increase dizziness or sildenafil levels respectively, so patients should be counselled to avoid excess alcohol and grapefruit around dosing.
| Drug/Class | Risk | Clinical Action |
|---|---|---|
| Nitrates | Severe hypotension | Contraindicated—do not coadminister |
| Alpha‑blockers / Antihypertensives | Orthostatic hypotension | Start low, monitor BP after first dose |
| Potent CYP3A4 inhibitors | Increased sildenafil exposure | Avoid or reduce dose; specialist advice |
| MAO inhibitors / Other SSRIs | Serotonin syndrome | 14‑day washout after MAOI; avoid combinations of multiple SSRIs |
Cultural Perceptions And Patient Habits In Australia
A common worry is embarrassment about asking for sexual medicines, especially outside cities.
Australian attitudes tend to view sexual health as private and stigma can delay help‑seeking, particularly in rural and Indigenous communities.
Price sensitivity is high and many consumers compare offers from discount chains such as Chemist Warehouse and Priceline or seek online pharmacies and telehealth services.
Community pharmacists—including chains and independents—remain trusted first contacts for questions about sildenafil and dapoxetine.
Telehealth has improved access for men in remote areas but raises concerns about continuity of care and thorough medication screening in single‑visit models.
| Setting | Access Pattern |
|---|---|
| Urban | Multiple suppliers, walk‑in GP and pharmacy access; price comparison between chains |
| Rural / Remote | Higher telehealth uptake, possible reliance on online importation, continuity of care concerns |
Availability And Pricing Patterns (Australia)
People often check whether the fixed combination is subsidised on the PBS.
Fixed‑dose combination products are generally not PBS‑listed and often enter Australia via private importation or online suppliers when supplied.
Sildenafil monotherapy and dapoxetine monotherapy may have different registration and subsidy statuses, but combined products commonly attract full private cost.
Major retail chains stock sildenafil monotherapy more frequently, while fixed combinations are more commonly obtained through online or overseas pharmacies and telehealth providers.
Rural patients may face higher effective costs due to limited supplier options and shipping charges for private imports.
| Channel | Typical Pricing Pattern |
|---|---|
| PBS (where applicable) | Often not applicable for fixed combinations; monotherapy coverage varies |
| Chain Pharmacies | Competitive retail pricing for sildenafil monotherapy; combos less commonly stocked |
| Online / Overseas Suppliers | Private cost, often lower unit price but importation/regulatory risks |
Note: In our online pharmacy, viagra with dapoxetine is available without a prescription, with discreet delivery to Australia in 5-14 days.
Comparable Medicines And Preferences
Many men ask whether other PDE5 inhibitor + dapoxetine combos are better or safer.
Alternatives on the market include tadalafil + dapoxetine (brands such as Tadapox or Super Vidalista) and vardenafil + dapoxetine combinations.
Monotherapy with sildenafil (e.g. Viagra) or dapoxetine (e.g. Priligy) remains standard first‑line depending on whether ED or PE is the dominant problem.
Pros of combinations: single‑tablet convenience and better simultaneous control of ED and PE for selected patients.
Cons: higher overall side‑effect burden, more drug interactions and variable regulatory status in some jurisdictions.
| Option | Pros | Cons |
|---|---|---|
| Sildenafil + Dapoxetine | Fast onset, well studied in trials | Shorter duration vs tadalafil; interaction risk |
| Tadalafil + Dapoxetine | Longer duration of action (tadalafil) | Longer effect may not suit all; similar interaction profile with dapoxetine |
| Monotherapy | Lower cumulative side effects; PBS subsidy possible | May not control both ED and PE simultaneously |
FAQ — Common Australian Patient Questions
- Can I take Viagra with Priligy?
Combining sildenafil (Viagra) and dapoxetine (Priligy) is a recognised pharmacological approach to treat coexisting ED and PE; a combined tablet exists but confirm local registration and get a prescription or clinical assessment before use, especially if you take nitrates or have significant heart disease.
- How long before sex should I take it?
Take the usual combined dose 1–3 hours before intercourse for sildenafil + dapoxetine combinations and do not exceed one dose in any 24‑hour period.
- Will PBS cover it?
Most fixed‑dose combinations are not PBS‑listed and will attract private cost; check PBS listings and discuss monotherapy subsidy options with a GP or pharmacist.
- What are the red flags?
Seek urgent medical care for priapism lasting over 4 hours, severe chest pain or fainting, and signs of serotonin syndrome such as high fever, agitation, tremor or loss of consciousness.
Guidelines For Proper Use And Pharmacy Counselling
Patients want clear, practical counselling before they take a combined tablet.
Pharmacist‑led counselling should start with a full medical history focusing on cardiovascular risk, psychiatric medications and current use of nitrates or MAO inhibitors.
Perform medication reconciliation and advise on the on‑demand dosing schedule, emphasising not to exceed one dose per 24 hours.
Explain common side effects such as headache, flushing, nausea, dizziness, visual changes and somnolence, and advise patients on when to seek urgent care.
Storage advice: keep tablets in original blister at 15–30°C, away from moisture and direct sunlight.
For rural and telehealth patients, ensure a documented follow‑up plan with a local GP or pharmacist, obtain informed consent for any unregistered products and encourage reporting of adverse events to the TGA.
Stepwise Counselling Checklist
- Confirm contraindications: nitrates, unstable cardiac disease, severe hepatic/renal impairment, psychiatric instability.
- Review current medicines for CYP3A4 inhibitors, MAOIs and serotonergic agents.
- Explain dosing: take 1–3 hours before sex; do not exceed once in 24 hours.
- Advise on side effects, red flags and avoidance of excessive alcohol.
- Document counselling and follow-up plan; report AEs to the TGA where appropriate.
Patient Leaflet Template (Short)
- What It Is: A tablet combining sildenafil and dapoxetine for men with both ED and PE.
- How To Take: One tablet 1–3 hours before sexual activity; max once per 24 hours.
- Do Not Take: With nitrates or if you have unstable heart disease; tell your pharmacist about antidepressants or MAOIs.
- Store: 15–30°C in the blister pack; keep away from children.
- Seek Help: For erection >4 hours, severe chest pain, fainting or signs of serotonin syndrome.
Delivery Across Australia
| City | Region | Delivery Time |
|---|---|---|
| Sydney | New South Wales | 5-7 days |
| Melbourne | Victoria | 5-7 days |
| Brisbane | Queensland | 5-7 days |
| Perth | Western Australia | 5-7 days |
| Adelaide | South Australia | 5-7 days |
| Canberra | Australian Capital Territory | 5-7 days |
| Hobart | Tasmania | 5-7 days |
| Darwin | Northern Territory | 5-9 days |
| Gold Coast | Queensland | 5-9 days |
| Newcastle | New South Wales | 5-9 days |
| Wollongong | New South Wales | 5-9 days |
| Sunshine Coast | Queensland | 5-9 days |
| Geelong | Victoria | 5-9 days |
| Cairns | Queensland | 5-9 days |
| Townsville | Queensland | 5-9 days |