Imipramine

The healthdirect page for Tofranil lists imipramine hydrochloride for two conditions: major depression, and nocturnal enuresis in children aged 5 and above when no organic cause is found. In the Tofranil consumer medicine information, imipramine is described as a tricyclic antidepressant.

This listing shows imipramine 25 mg, 50 mg and 75 mg. It does not name the manufacturer of the product supplied, so check the label on the pack you receive and confirm with your prescriber or pharmacist that it matches your prescription.

Compare packs of the same strength. These examples are for 75 mg and are calculated from the listed prices at the shop’s Australian-dollar rate on 9 October 2026, before delivery or other checkout charges.

Set against the 30-unit pack, one unit costs about 22.0% less in the pack of 60 and about 28.0% less in the pack of 120.

A lower price per unit means a larger upfront payment. Choose only the quantity and strength appropriate to your prescription, and check the expiry date. Prices can change, so confirm the current pack price before ordering.

Tofranil reaches Australia through Amdipharm Mercury (Australia) Pty Ltd as sugar-coated tablets of 10 mg and 25 mg. Healthdirect classes it as a Schedule 4 Prescription Only Medicine with a PBS subsidy as at 1 October 2026. In Australia, the 50 mg and 75 mg strengths on this listing are not registered as Tofranil.

According to the Tofranil leaflet, it may be 4 to 6 weeks before an improvement is felt.

The leaflet rules out Tofranil for anyone allergic to imipramine or to another tricyclic antidepressant, for people taking a monoamine oxidase inhibitor and for those recovering from a recent heart attack. After an MAOI is stopped, a gap of two weeks is needed before starting imipramine.

Imipramine carries a risk of suicidal thoughts, especially in young people, and the leaflet says to contact a doctor immediately if these occur. It should not be stopped without first talking to the doctor. People with glaucoma, trouble passing urine, a seizure history or heart disease need extra care. The leaflet recommends steering clear of alcohol and not driving until your response to imipramine is known. Healthdirect notes particular risks for people older than 65 that are worth raising with a doctor, and advises asking a doctor or pharmacist about use in pregnancy.

Common effects named in the leaflet are sleepiness, dizziness, dry mouth, constipation, putting on weight, sexual dysfunction and blurred vision. More serious are allergic reactions, an uneven heartbeat, severe confusion and uncontrolled movements. The leaflet also flags interactions with MAOIs, medicines for blood pressure, SSRIs, medicines for epilepsy, warfarin, certain cold remedies and nicotine products.

Healthdirect advises storing Tofranil below 30 °C and protecting it from moisture. Follow the storage directions on the pack you receive.

Standard delivery: 14–22 days. Express tracked delivery: 7–14 days, with the tracking number sent by email. These are estimated delivery times, not guaranteed arrival dates.

The Australian delivery options above apply to the destinations below. A city listing does not indicate a physical pharmacy branch or local stock.